Kallmann syndrome

Kallmann syndrome is a condition of low GnRH with anosmia. Embryologically the neurons which migrate to the hypothalamus start at the same place as those which become smell receptors. The patient turns out small with small genitals. Much psychological impact (and they can't smell their own body odour..) Treatment is by hormone replacement, and GnRH infusion pumps can help with subfertility issues. Named after a german geneticist. Two 'n's