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caffeine fix - Dr Peter Windross 2009 (img Wikipedia)
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Getting to grips with endocrine. Hormones and steroids
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Syndromes for fun

Nelson's syndrome

Described by an American endocrinologist in the 1960's

This is where a pituitary adenoma sitting quietly, suppressed by Cushing's syndrome comes to life. After bilateral adrenalectomy, this beast is unleashed causing local squashing and increased pigmentation (increased ACTH and Melanocyte stimulating hormone release)